Ivermectin may have some negative effects on female fertility, including:

Decreased egg production
In one study, all dosages of ivermectin significantly decreased egg production, with no eggs produced at 1.0 microgram/ml. The study also found a negative correlation between the dose rate and the number of eggs produced per female.

Delayed fertility
In another study, a single oral dose of ivermectin reduced fecundity and fertility in Anopheles arabiensis, with a delayed effect on fertility. For example, on day 13, mosquitoes fed on treated volunteers had a hatching rate of 90.5%, compared to 92.5% in the control group.

Other effects
Some studies have also reported other undesirable effects of ivermectin on fertility, such as slight fertility disturbances, a partial effect on meiosis, and slightly decreased weights of the testis, epididymis, and accessory sex glands.

Pregnancy outcome after inadvertent ivermectin treatment during community-based distribution - ScienceDirect
Dec 15, 1990

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